Sex differences in NK cell immunity against pancreatic cancer; androgen receptor pathways induce senescence in prostate cancer; repeat-associated ataxias analyzed by long-read sequencing; key genomic, metabolic, and ethical advances reported.

Arlt E, Bley N, Rausch A, Hauser S, Pietzsch J, Misiak D, Liehr T, Kankel S, Dautz T, Dreher L, Kǒng X, Kielstein H, Bazwinsky-Wutschke I. Sex determines the natural killer cell-mediated immunity against pancreatic cancer. Oncoimmunology 2026, 15: 2645298

Atri Roozbahani G, Heidari Horestani M, Schindler K, Kallenbach J, Baniahmad A. Induction of cellular senescence by androgen receptor agonist or antagonist is mediated via two novel common DYRK1A-DREAM and cyclin G2 signaling pathways in castration-resistant prostate cancer. J Adv Res. 2026, 80:371-392.

Asar DY, Kankel S, Keller DT, Hardt KS, Buhl EM, Liehr T, Weiskirchen R. Comprehensive cytogenetic and genomic profiling of the murine AML12 (Alpha Mouse Liver 12) hepatocyte cell line. Cells 2026, 15, 390

Batalli A, Liehr T, Temaj G. Behçet's disease: A comprehensive overview of symptoms, pathology, genetics, and treatment. J Mother Child. 2026, 30:1-10.

Bock A, Schurig M, Willoughby M, Mirecki A, Seemann E, Lohachova K, Katona I, Mittag S, Liebmann L, Franzka P, Heidari Horestani M, Khundadze M, Mosler T, Louie T, de Visser M, Weterman MAJ, Kiehntopf M, Beetz C, Nietzsche S, Huber O, Weis J, Kessels MM, Bhaskara RM, Qualmann B, Đikić I, Hübner CA. REEP1 accumulation disrupts ER integrity and drives spinal motoneuron degeneration in distal hereditary motor neuropathy. Adv Sci (Weinh). 2026, 13:e11483.

Erdmann H, Schaub A, Lucas MC, Scholz V, Benet-Pagès A, Becker K, Dineiger C, Mayer V, van Buren I, Breithausen E, Akbari K, Cordts I, Sauer M, Schneider C, Krakowsky R, Schnabel F, Dunker K, Fabritius L, Gerb J, Grabova D, Möhwald K, Näher M, Steinmetz K, Thiessen F, Jäck A, Schneider-Gold C, Zittel S, Petersen C, Schreyer I, Mämecke L, Wilfling S, Wunderlich G, Brenner D, Hellenbroich Y, Muhle K, Huchtemann T, Claus I, Klopstock T, Strupp M, Levin J, Höglinger GU, Huppert D, Becker-Bense S, Filippopulos F, Kilpert F, Leitão E, Kaya S, Depienne C, Schöberl F, Neuhann T, Holinski-Feder E, Zwergal A, Abicht A. Repeat-associated ataxias in a German patient cohort analysed by targeted parallel long-read sequencing. Brain. 2026 Mar 5;149(3):993-1006.

Hennings JC, Murthy KS, Picard N, Cabrita I, Böhm D, Huebner AK, Krause ME, Gentsch GJ, Shah V, Baraka-Vidot J, Khundadze M, Schmerler D, Kiehntopf M, Stauber T, Böckenhauer D, Jentsch TJ, Bachmann S, Franke C, Schermer B, Eladari D, Chambrey R, Hübner CA. Metabolic acidosis causes a Fanconi-like syndrome with intracellular trafficking defects and proximal tubule dysfunction. Sci Transl Med. 2026, 18: eads6299.

Kavaja F, Liehr T, Temaj G. MedicalGenetic architecture of obesity and advances in precision pharmacotherapy: A comprehensive review. Acta Biochim Pol 73:15484.

Liehr T. Challenges and ethical issues related to non-invasive prenatal testing (NIPT). OBM Genetics 2026; 10: 2601332.

Müller-Schiffmann A, Torres F, Kitaygorodskyy A, Ramani A, Alatza A, Tschirner SK, Orts J, Haltrich A, Prikulis I, Yu S, Dey D, Mallesh S, Prasad D, Solas D, Bader V, Rozemuller A, Wray S, Gopalakrishnan J, Riek R, Lingappa VR, Korth C. Oxidized MIF is an Alzheimer's disease drug target relaying external risk factors to tau pathology. Cell Rep Med. 2026, 7:102520.

Rincic M, Kopic J, Klein V, Krsnik Z, Liehr T, Giesselmann S, Kurth I, Kraft F. Structural variations in evolutionary novel genomic regions: New insights into neurodevelopmental disorders by long-read DNA sequencing. Mol Med. 2026, 32:17.

Taheri M, Baniahmad A. Response to letter to the editor. Int J Surg. 2026, 112:2199.

Liehr T. Fluorescence in situ Hybridization (FISH) – Application Guide, 3nd Ed., Springer, Berlin, 2026ISBN: 978 1071651490

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Source: https://www.uniklinikum-jena.de/humangenetik/Publikationen/2026.html
sdDatePublished: 2026-04-25T05:12:00Z
Topics: disease and condition, medical research, genetics, health treatment and procedure, ethics, health care provider
Locations: Berlin